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Welcome to fioricethere.com, your trusted source of prescription medications. fioricethere.com only employs highly qualified pharmacists and us licensed doctors. As you know, all US licensed pharmacists dare not send you prescriptions without valid US doctors’ prescriptions, besides, they can not send you prescriptions without the lawyer’s suggestion.

We all know DEA list fioricet (Butalbital, Acetaminophen, caffeine ) as Exempt Prescription and not controlled substance.

All Pharmacies associated are licensed to distribute in the states, you can be 100% sure to receive the same quality medication that you get from your local drug stores. To assure confidentiality and privacy our US licensed Pharmacy will fill and ship your prescription in a discreet package.

The US licensed pharmacies in our network never sell controlled substances. We will send you order ID and tracking ID together within two business days after you placed your orders. Please ignore any call from call centers and we never call customers to refill orders.

Upon receiving a valid prescription of the product you fill.  Our US licensed pharmacies will check your address and health conditions. If everything is OK, the information will delivered to a US licensed doctor, after the doctor reviewed your health conditions and approved it, it will send back to the pharmacies and the US licensed pharmacists will review it and approve the prescriptions. The last step is to print label and issue tracking ID. At least six steps will be involved to fill your order. We cannot stop the fill process once it begins.

Fioricet is the best headache reliever. By patient experience, it is valid for tension headache, migraine, cluster headache, and all kinds of headaches.

White Fioricet oblong
White Fioricet oblong

We have listed the detail Fioricet information, please check presentation version fioricet or pdf version of Fioricet.

Fioricet Precautions

Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use Fioricet if you are allergic to acetaminophen, butalbital, or caffeine, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.

To make sure Fioricet is safe for you, tell your doctor if you have:

      • liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;
      • kidney disease;
      • asthma, sleep apnea, or other breathing disorder;
      • stomach ulcer or bleeding;
      • a history of skin rash caused by any medication;
      • a history of mental illness or suicidal thoughts; or
      • if you use medicine to prevent blood clots.

It is not known whether Fioricet will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Pregnancy Category C

Animal reproduction studies have not been conducted with this combination product. It is also not known whether butalbital, acetaminophen and caffeine can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. This product should be given to a pregnant woman only when clearly needed.

Nonteratogenic Effects

Withdrawal seizures were reported in a two-day-old male infant whose mother had taken a butalbitalcontaining drug during the last two months of pregnancy. Butalbital was found in the infant’s serum. The  infant was given phenobarbital 5 mg/kg, which was tapered without further seizure or other withdrawal symptoms.

Nursing Mothers

Caffeine, barbiturates and acetaminophen are excreted in breast milk in small amounts, but the significance of their effects on nursing infants is not known. Because of potential for serious adverse reactions in nursing infants from butalbital, acetaminophen and caffeine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Fioricet is a combination medication of butalbital apap caffeine commonly used to treat tension headaches but doctors also recommend it for recurring migraines.

Fioricet is a combination medication commonly used to treat tension headaches but doctors also recommend it for recurring migraines.

Acetaminophen is used to decrease the pain associated with muscular tension and caffeine increases the efficiency of the pain-killing effect.

The last constituent of Fioricet is butalbital, a powerful sedative having the property to reduce anxiety and induce relaxation. This barbiturate is also responsible for the sleepiness appearing after Fioricet intake. Fioricet is available as tablets for oral administration, to be taken whole, by mouth, with or without food.

What is the dosage of Fioricet and how to take it?

The recommended dosage is of 1-2 tablets every 4 hours or as the doctor prescribes. Fioricet treatments can cause nausea and this is why most patients prefer to take this medication without food. Talking to the doctor about the nausea problem could lead to finding out essential information on how to reduce this unwanted effect. In fact, he/she can prescribe antihistamines for the nausea but there is also the possibility of lying down one hour after taking the medication.

The dosage for Fioricet is adapted according to each patient and the medical condition.

Throughout the entire period of the treatment, the doctor will monitor constantly the progress of the patient and the general response to the administration of the drug.

Fioricet is available as tablets for oral administration, to be taken whole, by mouth, with or without food.

When to take Fioricet ?

One of the side-effects caused by Fioricet is drowsiness. There are a lot of patients who report to the doctor complaining of day-time somnolence and in many cases the dosage of Fioricet is lowered. By going to the doctor, you can find out all there is to be known about Fioricet. You will be instructed to take it as soon as the first symptoms of tension headaches appear.

Fioricet is prescribed with extreme caution and medical specialists advise against using this medication for prolonged periods of time and in high doses.

It may cause dependence and severe withdrawal symptoms if the treatment is stopped of all a sudden. These symptoms are extremely varied, including flu-like symptoms with running nose and watery eyes.

How to prevent withdrawal syndromes ?

It may cause dependence and severe withdrawal symptoms if the treatment is stopped of all a sudden. These symptoms are extremely varied, including flu-like symptoms with running nose and watery eyes.

At the same time, there are patients who experience more serious symptoms with abnormal behavior, mental confusion and seizures.

The best thing to prevent withdrawal syndromes is to ask your doctor to reduce the dosage gradually.

You can also ask about the addiction potential presented by Fioricet and you will certainly be informed that this medication should not be taken in larger quantities or more frequently than indicated. Regular checkups are a must when you follow a treatment with Fioricet.

Talk to your doctor if you have started to use more than the usual dosage, if you notice the headaches to have become worse or if they appear often. Only a healthcare professional can decide if you need dosage adjustment or special tests performed in order to determine the cause of your headaches. Never try to solve these problems by yourself and do not believe the higher doses of this medication will do the trick.

What is the damages of butalbital ?

Barbiturate overdosing is likely to cause mental confusion, comatose states, sever fatigue, hallucinations and dyspnea. The treatment must be applied urgently, as butalbital can affect the vital centers of the brain.

What is the damage of caffeine ?

As for caffeine, high doses can lead to seizures, excessive perspiration and severe diarrhea. You can certainly understand that Fioricet is not something you take without consulting your doctor.

What should you do before you take generic fioricet ?

Before taking the medication, it is for the best that you tell your doctor if you have a history of substance abuse, alcohol addiction or if you have ever suffered from respiratory disease. Depression, liver disease and porphyria should also be mentioned.

Porphyria is a severe metabolic disorder and butalbital is not recommended to be used in such cases.

Fioricet can also interact with certain types of medication, including blood thinners, benzodiazepines, narcotic pain medication and tricyclic antidepressants. Be sure to discuss all these aspects with your doctor.

Remember, butalbital has a powerful effect on the central nervous system and this effect might be enhanced if you take MAO inhibitors at the same time.

Acetaminophen Mechanism of Action

Paracetamol (acetaminophen) is generally considered to be a weak inhibitor of the synthesis of prostaglandins (PGs). However, the in vivo effects of paracetamol are similar to those of the selective cyclooxygenase-2 (COX-2) inhibitors. Paracetamol also decreases PG concentrations in vivo, but, unlike the selective COX-2 inhibitors, paracetamol does not suppress the inflammation of rheumatoid arthritis.

It does, however, decrease swelling after oral surgery in humans and suppresses inflammation in rats and mice. Paracetamol is a weak inhibitor of PG synthesis of COX-1 and COX-2 in broken cell systems, but, by contrast, therapeutic concentrations of paracetamol inhibit PG synthesis in intact cells in vitro when the levels of the substrate arachidonic acid are low (less than about 5 mumol/L).

When the levels of arachidonic acid are low, PGs are synthesized largely by COX-2 in cells that contain both COX-1 and COX-2. Thus, the apparent selectivity of paracetamol may be due to inhibition of COX-2-dependent pathways that are proceeding at low rates.

This hypothesis is consistent with the similar pharmacological effects of paracetamol and the selective COX-2 inhibitors. COX-3, a splice variant of COX-1, has been suggested to be the site of action of paracetamol, but genomic and kinetic analysis indicates that this selective interaction is unlikely to be clinically relevant.

There is considerable evidence that the analgesic effect of paracetamol is central and is due to activation of descending serotonergic pathways, but its primary site of action may still be inhibition of PG synthesis.

The action of paracetamol at a molecular level is unclear but could be related to the production of reactive metabolites by the peroxidase function of COX-2, which could deplete glutathione, a cofactor of enzymes such as PGE synthase.

Fioricet Mechanism of Action

Fioricet Mechanism of action
Fioricet Mechanism of action

Butalbital exerts a generalized depressant effect on the central nervous system and, in very high doses, has peripheral effects.

Acetaminophen has analgesic and antipyretic effects mediated by a metabolite that acts at cannabinoid receptors. Caffeine is thought to produce constriction of cerebral blood vessels and serves to counteract the sedative effect of butalbital.

Butalbital has a half-life of about 35 hours. Acetaminophen has a half-life of about 1.25 to 3 hours, but may be increased by liver damage and after an overdose. Caffeine has a half-life of about 2.5 to 4.5 hours.

Fioricet Ingredient

Fioricet Ingredient
Fioricet Ingredient

Is Fioricet Addictive?

Although it’s only a prescription headache medication, Fioricet has the potential to cause addiction. If a person follows their prescription guidelines and uses the medication correctly, the risks of addiction are low.

However, if someone takes too much Fioricet, they may develop tolerance to its effects. A person with tolerance to a certain dose of Fioricet will require higher doses of the medication to alleviate their headaches.

When a person with tolerance starts to take more Fioricet, possibly by obtaining more prescriptions, they may eventually become dependent on it. In other words, they may feel unable to get through the day without taking Fioricet, and if they stop, they will experience symptoms of withdrawal. These symptoms arise because their body has grown accustomed to Fioricet in high doses.

If a Fioricet-dependent person attempts to weather withdrawal alone, it’s likely they will take Fioricet again just to relieve the symptoms. This is a hallmark characteristic of addiction. Anyone who compulsively abuses Fioricet to avoid withdrawal likely has an addiction to Fioricet. Additionally, people with an addiction to Fioricet will experience cravings for the medication which further compel them to keeping using it.

Moreover, the ingredient butalbital is an addictive substance in its own right. Butalbital can cause someone to “get high” because it’s a central nervous system depressant. Since butalbital is part of Fioricet, it is possible for someone to abuse Fioricet as a recreational drug. At high doses, Fioricet can intoxicate a person in a manner similar to alcohol. People who abuse Fioricet for this purpose have as much of a risk of developing an addiction as they would have if they repeatedly use an illegal drug.

The Symptoms of Fioricet Withdrawal

In most cases, Fioricet withdrawal lasts anywhere from 8 hours to three days after the last dose. Withdrawal is the biggest obstacle to overcoming dependence on Fioricet, which is why rehab centers provide detox programs so that people can safely undergo the withdrawal cycle without the risk of relapse. It is best to undergo withdrawal under medical supervision because some withdrawal symptoms are dangerous.

Rebound headaches are the most common symptoms of Fioricet withdrawal. Other symptoms of withdrawal include:

      • Anxiety
      • Dizziness
      • Insomnia
      • Muscle spasms
      • Nausea and vomiting
      • Rapid emotional changes
      • Seizures (in rare cases)
      • Tremors
      • Weakness